Pub. Date : 2009 Jun
PMID : 19233181
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | BACKGROUND & AIMS: Variants in the cytochrome P450 2C9 (CYP2C9) gene are associated with impaired metabolism of celecoxib. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | BACKGROUND & AIMS: Variants in the cytochrome P450 2C9 (CYP2C9) gene are associated with impaired metabolism of celecoxib. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 4 | CONCLUSIONS: The greater efficacy of high-dose celecoxib, compared with the low-dose, in preventing colorectal adenoma appears confined to individuals with slow metabolizer (CYP2C9*3) genotypes. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |