PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19233181-0 2009 Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma. Celecoxib 51-60 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 0-19 19233181-1 2009 BACKGROUND & AIMS: Variants in the cytochrome P450 2C9 (CYP2C9) gene are associated with impaired metabolism of celecoxib. Celecoxib 116-125 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 39-58 19233181-1 2009 BACKGROUND & AIMS: Variants in the cytochrome P450 2C9 (CYP2C9) gene are associated with impaired metabolism of celecoxib. Celecoxib 116-125 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 60-66 19233181-10 2009 CONCLUSIONS: The greater efficacy of high-dose celecoxib, compared with the low-dose, in preventing colorectal adenoma appears confined to individuals with slow metabolizer (CYP2C9*3) genotypes. Celecoxib 47-56 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 174-180