Pub. Date : 2009 May
PMID : 19188434
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High glucose suppresses epidermal growth factor receptor/phosphatidylinositol 3-kinase/Akt signaling pathway and attenuates corneal epithelial wound healing. | Glucose | epidermal growth factor receptor | Homo sapiens |
| 2 | This study investigated the effects of high glucose on epidermal growth factor receptor (EGFR) signaling and on epithelial wound healing in the cornea. | Glucose | epidermal growth factor receptor | Homo sapiens |
| 3 | RESULTS: High glucose impaired ex vivo epithelial wound healing and disturbed cell responses and EGFR signaling to wounding. | Glucose | epidermal growth factor receptor | Homo sapiens |
| 4 | CONCLUSIONS: High glucose, likely through ROS, impairs the EGFR-phosphatidylinositol 3-kinase/Akt pathway, resulting in delayed corneal epithelial wound healing. | Glucose | epidermal growth factor receptor | Homo sapiens |