Title : Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cells.

Pub. Date : 2008

PMID : 19061498






1 Functional Relationships(s)
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1 However, pretreatment with 10058-F4 (an inhibitor of c-Myc transcriptional activity) or PD98059 (an inhibitor of ERK1/2) suppressed c-Myc expression and ERK1/2 phosphorylation, and inhibited cell cycle promotion by TGFbeta1. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one transforming growth factor, beta 1 Rattus norvegicus