Title : Na+/K+-ATPase-mediated signal transduction and Na+/K+-ATPase regulation.

Pub. Date : 2008 Dec

PMID : 19049666






2 Functional Relationships(s)
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Protein Name
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1 Low concentration of ouabain binding to Na(+)/K(+)-ATPase activates Src/epidermal growth factor receptor complex to initiate multiple signal pathways, which include PLC/IP3/CICR, PI3K, reactive oxygen species (ROS), PLC/DG/PKC/Raf/MEK/ERK1/2, and Ras/Raf/MEK/ERK1/2 pathways. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 Low concentration of ouabain binding to Na(+)/K(+)-ATPase activates Src/epidermal growth factor receptor complex to initiate multiple signal pathways, which include PLC/IP3/CICR, PI3K, reactive oxygen species (ROS), PLC/DG/PKC/Raf/MEK/ERK1/2, and Ras/Raf/MEK/ERK1/2 pathways. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens