Title : A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response.

Pub. Date : 2009 Apr 23

PMID : 19029442






2 Functional Relationships(s)
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1 A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response. KW 2449 fms related receptor tyrosine kinase 3 Homo sapiens
2 KW-2449 is a novel multitargeted kinase inhibitor that induces cytotoxicity in Molm14 cells (which harbor an FLT3/ITD mutation). KW 2449 fms related receptor tyrosine kinase 3 Homo sapiens