Title : Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.

Pub. Date : 2009 Aug

PMID : 18931933






2 Functional Relationships(s)
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1 Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A. Thioctic Acid AKT serine/threonine kinase 1 Rattus norvegicus
2 (R)-alpha-lipoic acid (LA), a dithiol compound with antioxidant properties, is effective against age-related increases in oxidative stress and has been used to improve glucose utilization through insulin receptor (IR) pathway-mediated Akt phosphorylation. Thioctic Acid AKT serine/threonine kinase 1 Rattus norvegicus