Title : Tumor necrosis factor-alpha induces renal vasoconstriction as well as natriuresis in mice.

Pub. Date : 2008 Dec

PMID : 18922887






3 Functional Relationships(s)
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1 However, TNF-alpha induced an increase in RBF and caused attenuation of the GFR reduction in mice pretreated with superoxide (O(2)(-)) scavenger tempol (2 microg.g(-1).min(-1); n = 6). Superoxides tumor necrosis factor Mus musculus
2 However, TNF-alpha induced an increase in RBF and caused attenuation of the GFR reduction in mice pretreated with superoxide (O(2)(-)) scavenger tempol (2 microg.g(-1).min(-1); n = 6). Superoxides tumor necrosis factor Mus musculus
3 These data suggest that TNF-alpha induces renal vasoconstriction and hypofiltration via enhancing the activity of O(2)(-) and thus reducing the activity of NO. Superoxides tumor necrosis factor Mus musculus