PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18922887-10 2008 However, TNF-alpha induced an increase in RBF and caused attenuation of the GFR reduction in mice pretreated with superoxide (O(2)(-)) scavenger tempol (2 microg.g(-1).min(-1); n = 6). Superoxides 114-124 tumor necrosis factor Mus musculus 9-18 18922887-10 2008 However, TNF-alpha induced an increase in RBF and caused attenuation of the GFR reduction in mice pretreated with superoxide (O(2)(-)) scavenger tempol (2 microg.g(-1).min(-1); n = 6). Superoxides 126-130 tumor necrosis factor Mus musculus 9-18 18922887-12 2008 These data suggest that TNF-alpha induces renal vasoconstriction and hypofiltration via enhancing the activity of O(2)(-) and thus reducing the activity of NO. Superoxides 114-118 tumor necrosis factor Mus musculus 24-33