Pub. Date : 2008 Nov 4
PMID : 18847222
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | There have been a number of studies monitoring reactive oxygen species (ROS) generation by copper and ascorbate that suggest that Abeta acts as a prooxidant producing H2O2. | Ascorbic Acid | amyloid beta precursor protein | Homo sapiens |
| 2 | Abeta does not silence the redox activity of Cu(2+/+) via chelation, but rather hydroxyl radicals produced as a result of Fenton-Haber Weiss reactions of ascorbate and Cu(2+) rapidly react with Abeta; thus the potentially harmful radicals are quenched. | Ascorbic Acid | amyloid beta precursor protein | Homo sapiens |
| 3 | Abeta does not silence the redox activity of Cu(2+/+) via chelation, but rather hydroxyl radicals produced as a result of Fenton-Haber Weiss reactions of ascorbate and Cu(2+) rapidly react with Abeta; thus the potentially harmful radicals are quenched. | Ascorbic Acid | amyloid beta precursor protein | Homo sapiens |