PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18847222-3 2008 There have been a number of studies monitoring reactive oxygen species (ROS) generation by copper and ascorbate that suggest that Abeta acts as a prooxidant producing H2O2. Ascorbic Acid 102-111 amyloid beta precursor protein Homo sapiens 130-135 18847222-8 2008 Abeta does not silence the redox activity of Cu(2+/+) via chelation, but rather hydroxyl radicals produced as a result of Fenton-Haber Weiss reactions of ascorbate and Cu(2+) rapidly react with Abeta; thus the potentially harmful radicals are quenched. Ascorbic Acid 154-163 amyloid beta precursor protein Homo sapiens 0-5 18847222-8 2008 Abeta does not silence the redox activity of Cu(2+/+) via chelation, but rather hydroxyl radicals produced as a result of Fenton-Haber Weiss reactions of ascorbate and Cu(2+) rapidly react with Abeta; thus the potentially harmful radicals are quenched. Ascorbic Acid 154-163 amyloid beta precursor protein Homo sapiens 194-199