Title : Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF.

Pub. Date : 2008 Aug

PMID : 18632822






4 Functional Relationships(s)
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1 The purpose of this study was to investigate the relationship between EGFR expression, DNA damage, and cytotoxicity in cells exposed to 111In-DTPA-hEGF. 111in-dtpa epidermal growth factor receptor Homo sapiens
2 METHODS: Breast cancer cell lines with a range of EGFR expression levels were exposed to 111In-DTPA-hEGF or gamma-radiation. 111in-dtpa epidermal growth factor receptor Homo sapiens
3 CONCLUSION: DNA damage caused by 111In-DTPA-hEGF correlates with the EGFR expression level of the exposed cells and with concentration, specific activity, and incubation time of 111In-DTPA-hEGF. 111in-dtpa epidermal growth factor receptor Homo sapiens
4 CONCLUSION: DNA damage caused by 111In-DTPA-hEGF correlates with the EGFR expression level of the exposed cells and with concentration, specific activity, and incubation time of 111In-DTPA-hEGF. 111in-dtpa epidermal growth factor receptor Homo sapiens