Pub. Date : 2008 Sep
PMID : 18562571
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcineurin inhibitor (CNI) withdrawal from a sirolimus-based immunosuppressive regimen may maximize the likelihood of long-term graft and patient survival by minimizing CNI-associated nephrotoxicity. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 2 | Calcineurin inhibitor (CNI) withdrawal from a sirolimus-based immunosuppressive regimen may maximize the likelihood of long-term graft and patient survival by minimizing CNI-associated nephrotoxicity. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 3 | Calcineurin inhibitor (CNI) withdrawal from a sirolimus-based immunosuppressive regimen may maximize the likelihood of long-term graft and patient survival by minimizing CNI-associated nephrotoxicity. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 4 | In this study, a lifetime Markov model was created to compare the cost-effectiveness of a sirolimus-based CNI withdrawal regimen (sirolimus plus steroids) with other common CNI-containing regimens in adult de novo renal transplantation patients. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 5 | In this study, a lifetime Markov model was created to compare the cost-effectiveness of a sirolimus-based CNI withdrawal regimen (sirolimus plus steroids) with other common CNI-containing regimens in adult de novo renal transplantation patients. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 6 | The model suggests that treatment with sirolimus plus steroids is more efficacious and less costly than regimens consisting of a CNI, mycophenolate mofetil, and steroids; therefore, CNI withdrawal not only shows potential for long-term clinical benefits but also is expected to be cost-saving over a patient"s life compared with the most commonly prescribed CNI-containing regimens. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |
| 7 | The model suggests that treatment with sirolimus plus steroids is more efficacious and less costly than regimens consisting of a CNI, mycophenolate mofetil, and steroids; therefore, CNI withdrawal not only shows potential for long-term clinical benefits but also is expected to be cost-saving over a patient"s life compared with the most commonly prescribed CNI-containing regimens. | Sirolimus | calcineurin binding protein 1 | Homo sapiens |