Protein Name calcineurin binding protein 1
Organism Homo sapiens
Gene ID 23523
Gene Symbol

CABIN1

UniProt Q9Y6J0 (CABIN_HUMAN), A0A024R1E5 (A0A024R1E5_HUMAN), A0A087WWW8 (A0A087WWW8_HUMAN)
Relationships Total Number of functionally related compound(s) : 118
Total Number of Articles : 456
Description

calcineurin binding protein 1

Gene Summary

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]

synonyms
  • calcineurin-binding protein cabin-1
  • calcineurin binding protein cabin 1
  • calcineurin inhibitor
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Properties