Title : Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes.

Pub. Date : 2008 Jun

PMID : 18391018






1 Functional Relationships(s)
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1 We show that exchange protein directly activated by cAMP (Epac), which functions as a guanine nucleotide exchange factor for the Ras-like GTPases Rap1 and Rap2, was required for cAMP-dependent stimulation of adipocyte differentiation. Guanine Nucleotides RAP1A, member of RAS oncogene family Homo sapiens