PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18391018-2 2008 We show that exchange protein directly activated by cAMP (Epac), which functions as a guanine nucleotide exchange factor for the Ras-like GTPases Rap1 and Rap2, was required for cAMP-dependent stimulation of adipocyte differentiation. Guanine Nucleotides 86-104 RAP1A, member of RAS oncogene family Homo sapiens 146-150