Pub. Date : 2008 Apr
PMID : 18375819
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BRAF that is activated by the common V600E and other mutations, as well as by upstream NRAS mutations, has been shown to require the molecular chaperone heat shock protein 90 (HSP90) for stabilization and is depleted by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG)]. | tanespimycin | B-Raf proto-oncogene, serine/threonine kinase | Homo sapiens |