Title : Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance.

Pub. Date : 2008 Feb 21

PMID : 18288188






2 Functional Relationships(s)
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1 After induction with insulin, phosphatidylinositol 3,4,5-trisphosphate recruits OGT from the nucleus to the plasma membrane, where the enzyme catalyses dynamic modification of the insulin signalling pathway by O-GlcNAc. phosphatidylinositol 3,4,5-triphosphate O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 After induction with insulin, phosphatidylinositol 3,4,5-trisphosphate recruits OGT from the nucleus to the plasma membrane, where the enzyme catalyses dynamic modification of the insulin signalling pathway by O-GlcNAc. phosphatidylinositol 3,4,5-triphosphate O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens