Pub. Date : 2008 Feb
PMID : 18005386
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bortezomib acts by targeting the proteasome, and--among other mechanisms--results in a reduced nuclear factor-kappa B (NF-kappaB) activity. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Bortezomib acts by targeting the proteasome, and--among other mechanisms--results in a reduced nuclear factor-kappa B (NF-kappaB) activity. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | In addition, coexposure of bortezomib and SAHA led to increased caspase-3, -8 and -9 activity, marked reduction of proteasome activity and decrease of NF-kappaB activity. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |