PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18005386-3 2008 Bortezomib acts by targeting the proteasome, and--among other mechanisms--results in a reduced nuclear factor-kappa B (NF-kappaB) activity. Bortezomib 0-10 nuclear factor kappa B subunit 1 Homo sapiens 95-117 18005386-3 2008 Bortezomib acts by targeting the proteasome, and--among other mechanisms--results in a reduced nuclear factor-kappa B (NF-kappaB) activity. Bortezomib 0-10 nuclear factor kappa B subunit 1 Homo sapiens 119-128 18005386-12 2008 In addition, coexposure of bortezomib and SAHA led to increased caspase-3, -8 and -9 activity, marked reduction of proteasome activity and decrease of NF-kappaB activity. Bortezomib 27-37 nuclear factor kappa B subunit 1 Homo sapiens 151-160