Title : Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus.

Pub. Date : 2007 Sep

PMID : 17870172






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 NMDA NR2A, calcium/calmodulin-dependent protein kinase IV (CaMKIV), cyclic AMP-responsive element binding protein 1 (CREB1), and BDNF were significantly up-regulated in the hippocampi of WT mice exposed to 9ppm of toluene, compared to the expressions observed in WT mice exposed to filtered air, but similar results were not observed in nude mice. Toluene cAMP responsive element binding protein 1 Mus musculus