Title : Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway.

Pub. Date : 2007 Jul

PMID : 17637928






1 Functional Relationships(s)
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Protein Name
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1 Mutation of tyrosine to serine at the 21st amino acid of the Bcl-2 protein BH4 domain resulted in a loss both of suppression of JNK1/2 phosphorylation and its anti-apoptotic function. Serine mitogen-activated protein kinase 8 Homo sapiens