Pub. Date : 2007 Jul 17
PMID : 17620609
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using rounds of mutagenesis coupled with in vivo screens for NRP production, we rapidly isolated variants of two different chimeric NRPSs with approximately 10-fold improvements in enzyme activity and product yield, including one that produces new derivatives of the potent NRP/polyketide antibiotic andrimid. | Polyketides | neuropilin 1 | Homo sapiens |
2 | Using rounds of mutagenesis coupled with in vivo screens for NRP production, we rapidly isolated variants of two different chimeric NRPSs with approximately 10-fold improvements in enzyme activity and product yield, including one that produces new derivatives of the potent NRP/polyketide antibiotic andrimid. | Polyketides | neuropilin 1 | Homo sapiens |