Title : Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells.

Pub. Date : 2007 Apr

PMID : 17534406






3 Functional Relationships(s)
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1 Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells. Testosterone tissue factor pathway inhibitor Homo sapiens
2 Testosterone at a physiologic concentration (30 nmol/L) increased the antigen levels of tPA and TFPI significantly (P < 0.05). Testosterone tissue factor pathway inhibitor Homo sapiens
3 The results demonstrated that testosterone at physiological concentrations may have a beneficial influence on the haemostatic system through enhancement of anticoagulant activity, resulting from stimulation of TFPI and tPA expression and inhibition of PAI-1 secretion by the endothelium. Testosterone tissue factor pathway inhibitor Homo sapiens