Pub. Date : 2007 Jun 1
PMID : 17462533
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. | Reactive Oxygen Species | epidermal growth factor receptor | Rattus norvegicus |
| 2 | These results suggest that (1) IGF-I induces EGFR activation through production of ROS and ROS-mediated Src activation in VSMCs, and (2) EGFR transactivation is required for IGF-I-induced VSMC proliferation. | Reactive Oxygen Species | epidermal growth factor receptor | Rattus norvegicus |
| 3 | These results suggest that (1) IGF-I induces EGFR activation through production of ROS and ROS-mediated Src activation in VSMCs, and (2) EGFR transactivation is required for IGF-I-induced VSMC proliferation. | Reactive Oxygen Species | epidermal growth factor receptor | Rattus norvegicus |