PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17351648-0 2007 Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells. Sirolimus 0-9 CD4 antigen Mus musculus 86-89 17351648-8 2007 Prolonged rapamycin treatment allowed for thymic generation of CD4(+)FoxP3(+) T cells, whereas treatment with cyclosporine led to a reduced generation of these cells. Sirolimus 10-19 CD4 antigen Mus musculus 63-66 17351648-9 2007 In conclusion, cyclosporine and rapamycin differentially affect homeostasis of CD4(+)FoxP3(+) T(REG) in vivo. Sirolimus 32-41 CD4 antigen Mus musculus 79-82