Protein Name | CD4 antigen |
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Organism | Mus musculus |
Gene ID | 12504 |
Gene Symbol | Cd4 |
UniProt | P06332 (CD4_MOUSE), Q3TSV7 (Q3TSV7_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
1594
Total Number of Articles : 2732 |
Description |
CD4 antigen |
Gene Summary |
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |