Title : Effects of heme oxygenase-1 expression on sterol homeostasis in rat astroglia.

Pub. Date : 2007 Mar 15

PMID : 17320768






1 Functional Relationships(s)
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1 In the current study, we demonstrated that transient transfection of rat astroglia with human (h)ho-1 cDNA for 3 days significantly decreased intracellular cholesterol concentrations and increased levels of four oxysterol species (measured by GC/MS) compared to untreated control cultures and HO-1-transfected cells exposed to the HO inhibitor, tin mesoporphyrin (SnMP). Oxysterols heme oxygenase 1 Homo sapiens