Pub. Date : 2007 May
PMID : 17283219
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thalidomide-induced cell death was dramatically reduced in HEFs and in embryonic limb buds by the use of inhibitors against Bmps, Dkk1, and Gsk3beta, a beta-catenin antagonist acting downstream of Dkk1 in the Wnt pathway. | Thalidomide | glycogen synthase kinase 3 beta | Homo sapiens |
| 2 | Most interestingly, blocking of Dkk1 or Gsk3beta dramatically counteracts thalidomide-induced limb truncations and microphthalmia. | Thalidomide | glycogen synthase kinase 3 beta | Homo sapiens |