Title : Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis.

Pub. Date : 2007 Feb 27

PMID : 17274632






2 Functional Relationships(s)
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1 RESULTS: Alpha-lipoic acid decreased actinomycinD/TNF-alpha-induced apoptosis, as did the antioxidants Trolox and N-acetylcysteine. Thioctic Acid tumor necrosis factor Rattus norvegicus
2 Alpha-lipoic acid but not other antioxidants protected against actinomycinD/TNF-alpha-induced apoptosis via phosphorylation of the insulin receptor. Thioctic Acid tumor necrosis factor Rattus norvegicus