PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17259562-5 2006 Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. Tamoxifen 195-204 epidermal growth factor receptor Homo sapiens 89-93 17259562-5 2006 Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. Tamoxifen 195-204 epidermal growth factor receptor Homo sapiens 181-185 17259562-5 2006 Here, we describe both non-genomic and genomic mechanisms of resistance to the selective EGFR tyrosine kinase inhibitor gefitinib (IRESSA), which we have identified initially in an EGFR-positive tamoxifen-resistant MCF-7 breast cancer cell line, but more recently in other EGFR-positive cancer types. Tamoxifen 195-204 epidermal growth factor receptor Homo sapiens 181-185