Title : TNF-alpha/IFN-gamma-induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling.

Pub. Date : 2007 Jan 15

PMID : 17091492






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TNF-alpha/IFN-gamma-induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling. Dinoprostone nitric oxide synthase 2 Rattus norvegicus
2 Pharmacological and RNA interference approaches further indicated the involvement of the receptor EP2 in PGE(2)-induced iNOS upregulation in T/I-treated astrocytes. Dinoprostone nitric oxide synthase 2 Rattus norvegicus
3 Quantitative real-time polymerase chain reaction and gel mobility shift assays also demonstrated that PGE(2) increased iNOS transcription through EP2-induced cAMP/protein kinase A (PKA)-dependent pathway. Dinoprostone nitric oxide synthase 2 Rattus norvegicus