Pub. Date : 2006 Oct
PMID : 17015054
6 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||
| 2 | We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||
| 3 | We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||
| 4 | We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||
| 5 | CONCLUSION: In this study the MDR1 1236TT, 2677TT, and 3435TT genotypes, along with the 1236-2677-3435 TTT haplotype, were associated with neuropsychiatric adverse effects of mefloquine in women. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||
| 6 | MDR1 polymorphisms may play an important role in predicting the occurrence of neuropsychiatric adverse effects of mefloquine, particularly in female travelers. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens | ||