PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17015054-0 2006 MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine. Mefloquine 80-90 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 17015054-2 2006 We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. Mefloquine 57-67 ATP binding cassette subfamily B member 1 Homo sapiens 109-113 17015054-2 2006 We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. Mefloquine 57-67 ATP binding cassette subfamily B member 1 Homo sapiens 114-119 17015054-2 2006 We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. Mefloquine 57-67 ATP binding cassette subfamily B member 1 Homo sapiens 158-172 17015054-9 2006 CONCLUSION: In this study the MDR1 1236TT, 2677TT, and 3435TT genotypes, along with the 1236-2677-3435 TTT haplotype, were associated with neuropsychiatric adverse effects of mefloquine in women. Mefloquine 175-185 ATP binding cassette subfamily B member 1 Homo sapiens 30-34 17015054-10 2006 MDR1 polymorphisms may play an important role in predicting the occurrence of neuropsychiatric adverse effects of mefloquine, particularly in female travelers. Mefloquine 114-124 ATP binding cassette subfamily B member 1 Homo sapiens 0-4