Title : p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy.

Pub. Date : 2006 Sep 20

PMID : 16932740






1 Functional Relationships(s)
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1 The underlying mechanism entails phosphorylation of EGFR at a short segment (amino acids 1002-1022) containing multiple serines and threonines, as well as phosphorylation of two Rab5 effectors, EEA1 and GDI. Serine epidermal growth factor receptor Homo sapiens