Title : In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: a novel mechanism of action?

Pub. Date : 2006 Oct 15

PMID : 16828825






1 Functional Relationships(s)
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1 The precursor substrate of CYP17, pregnenolone, was added to control and exposed H295R cells, and enzymatic production of DHEA was measured using a radioimmunoassay. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens