Pub. Date : 2006 Oct
PMID : 16828304
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, ioversol induced a decrease in the expression for bcl-2 mRNA and an increase for bax mRNA. | ioversol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 2 | In addition, irbesartan reversed the ioversol-induced increase in bax mRNA and decrease in bcl-2 mRNA. | ioversol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 3 | CONCLUSION: Ioversol induced NRK-52E cells apoptosis in a concentration- and time-dependant manner via an increase in oxidative stress and subsequent to the increase in mRNA expression for bax and reduction in bcl-2 mRNA. | ioversol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 4 | Irbesartan attenuated the ioversol-induced apoptosis in NRK-52E cells by reducing oxidative stress and reversing the enhancement of bax mRNA and the reduction in bcl-2 mRNA. | ioversol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |