Pub. Date : 2006 Feb
PMID : 16538045
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | On the other hand, 5-FU 20 mg/kg also caused a significant decline in the amount of produced TNF-alpha but it showed no apparent effects on the number of leukocytes and the body weight. | Fluorouracil | tumor necrosis factor | Mus musculus |
| 2 | These results indicate that LPS-induced TNF-alpha production is a more sensitive measure than leukocyte count used conventionally to detect the immunotoxicity of two anticancer drugs, CDDP and 5-FU, and suggest that it might be a more practical index for hazard identification in clinical treatment with anticancer drugs. | Fluorouracil | tumor necrosis factor | Mus musculus |