PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16538045-4 2006 On the other hand, 5-FU 20 mg/kg also caused a significant decline in the amount of produced TNF-alpha but it showed no apparent effects on the number of leukocytes and the body weight. Fluorouracil 19-23 tumor necrosis factor Mus musculus 93-102 16538045-5 2006 These results indicate that LPS-induced TNF-alpha production is a more sensitive measure than leukocyte count used conventionally to detect the immunotoxicity of two anticancer drugs, CDDP and 5-FU, and suggest that it might be a more practical index for hazard identification in clinical treatment with anticancer drugs. Fluorouracil 193-197 tumor necrosis factor Mus musculus 40-49