Title : Effect of intestinal CYP3A5 on postoperative tacrolimus trough levels in living-donor liver transplant recipients.

Pub. Date : 2006 Feb

PMID : 16424824






1 Functional Relationships(s)
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1 It has been reported that hepatic and intestinal cytochrome P450 (CYP) 3A4, CYP3A5 and P-glycoprotein affect the pharmacokinetics of tacrolimus, and that these proteins are associated with the large inter-individual variation in the pharmacokinetics of this drug. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens