PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16424824-1 2006 It has been reported that hepatic and intestinal cytochrome P450 (CYP) 3A4, CYP3A5 and P-glycoprotein affect the pharmacokinetics of tacrolimus, and that these proteins are associated with the large inter-individual variation in the pharmacokinetics of this drug. Tacrolimus 133-143 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 49-74