Title : Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids.

Pub. Date : 2005 Oct 15

PMID : 16249748






2 Functional Relationships(s)
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1 Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. Sirolimus ATP binding cassette subfamily B member 1 Homo sapiens
2 CYP3A5 (intron 3) and MDR1 (exons 12, 21, 26) genotypes were correlated to the adjusted trough concentrations and dose requirements for both sirolimus and tacrolimus. Sirolimus ATP binding cassette subfamily B member 1 Homo sapiens