Title : Paclitaxel induces the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 through a Cdk1-dependent mechanism.

Pub. Date : 2005 Jul 14

PMID : 15897904






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Paclitaxel induces the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 through a Cdk1-dependent mechanism. Paclitaxel cyclin dependent kinase 1 Homo sapiens
2 Taken together, our data suggest that PTX-increases the functional level of eIF-4E by promoting the hyperphosphorylation and release of 4E-BP1 through a cdk1-dependent mechanism. Paclitaxel cyclin dependent kinase 1 Homo sapiens