Title : In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazole.

Pub. Date : 2003

PMID : 15618748






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ABT exhibited the highest Ki value for CYP2C9-dependent diclofenac 4"-hydroxylation among those determined by this assay (Ki=3500 microM). diclofenac 4" cytochrome P450 family 2 subfamily C member 9 Homo sapiens