Pub. Date : 2004 Nov
PMID : 15607480
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Moreover, such binding in SERT-rich brain regions is reduced significantly by pretreatment with either citalopram or the cold compound itself, but not by nisoxetine or GBR 12935, thus demonstrating that [(11)C]AFE binding in the rat brain is saturable, specific and selective for the SERT. | Citalopram | solute carrier family 6 member 4 | Rattus norvegicus |
2 | Moreover, such binding in SERT-rich brain regions is reduced significantly by pretreatment with either citalopram or the cold compound itself, but not by nisoxetine or GBR 12935, thus demonstrating that [(11)C]AFE binding in the rat brain is saturable, specific and selective for the SERT. | Citalopram | solute carrier family 6 member 4 | Rattus norvegicus |
3 | Pretreatment of the baboon with citalopram (4 mg/kg) 20 min before radioactivity injection reduced the binding of [(11)C]AFE in all SERT-containing brain regions to the level in the cerebellum. | Citalopram | solute carrier family 6 member 4 | Rattus norvegicus |