Pub. Date : 2005 Feb 15
PMID : 15531749
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acrolein increased the release and subsequent activation of pro-MMP9. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |
| 2 | Acrolein increased MMP9 and decreased tissue inhibitor of metalloproteinase 3 (TIMP3), an endogenous inhibitor of ADAM17, transcripts. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |
| 3 | Together, these data suggest that acrolein induces MUC5AC expression via an initial ligand-dependent activation of EGFR mediated by ADAM17 and MMP9. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |
| 4 | In addition, a prolonged effect of acrolein may be mediated by altering MMP9 and TIMP3 transcription. | Acrolein | matrix metallopeptidase 9 | Homo sapiens |