Title : Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline.

Pub. Date : 2004 Apr

PMID : 15449725






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline. Terbutaline butyrylcholinesterase Homo sapiens
2 Both bambuterol and terbutaline inhibit BChE, but their affinities differ in human serum BChE variants (U, A, F, K and S) due to their positive charge. Terbutaline butyrylcholinesterase Homo sapiens
3 Terbutaline showed competitive reversible inhibition for all BChE variants. Terbutaline butyrylcholinesterase Homo sapiens
4 The affinity of all studied BChE variants for terbutaline was low, which suggests that terbutaline originating from bambuterol hydrolysis should not affect the hydrolysis of bambuterol by BChE. Terbutaline butyrylcholinesterase Homo sapiens
5 The affinity of all studied BChE variants for terbutaline was low, which suggests that terbutaline originating from bambuterol hydrolysis should not affect the hydrolysis of bambuterol by BChE. Terbutaline butyrylcholinesterase Homo sapiens