Title : Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload.

Pub. Date : 2004 Feb

PMID : 14610239






1 Functional Relationships(s)
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1 These results suggest that pressure-overload induces the up-regulation of AT(2) receptor expression in aortas via AT(1) receptor and thereby negatively modulates the vasoconstrictor sensitivity to Ang II, probably mediated by the mechanisms independent of the nitric oxide-cGMP system. Cyclic GMP angiotensinogen Rattus norvegicus