Title : AP-1 complex and c-fos transcription are involved in TPA provoked and trans-synaptic inductions of the tyrosine hydroxylase gene: insights into long-term regulatory mechanisms.

Pub. Date : 1992 Jun

PMID : 1383560






9 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 AP-1 complex and c-fos transcription are involved in TPA provoked and trans-synaptic inductions of the tyrosine hydroxylase gene: insights into long-term regulatory mechanisms. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
2 We have previously shown that the phorbol ester, TPA, which activates protein kinase C, causes, in PC12 cells, a transcriptional activation of tyrosine hydroxylase (TH), the key enzyme in catecholamine synthesis. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
3 We have previously shown that the phorbol ester, TPA, which activates protein kinase C, causes, in PC12 cells, a transcriptional activation of tyrosine hydroxylase (TH), the key enzyme in catecholamine synthesis. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
4 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
5 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
6 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
7 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
8 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus
9 Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA. Tetradecanoylphorbol Acetate tyrosine hydroxylase Rattus norvegicus