PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1383560-0	1992	AP-1 complex and c-fos transcription are involved in TPA provoked and trans-synaptic inductions of the tyrosine hydroxylase gene: insights into long-term regulatory mechanisms.	Tetradecanoylphorbol Acetate	53-56	tyrosine hydroxylase	Rattus norvegicus	103-123	
1383560-1	1992	We have previously shown that the phorbol ester, TPA, which activates protein kinase C, causes, in PC12 cells, a transcriptional activation of tyrosine hydroxylase (TH), the key enzyme in catecholamine synthesis.	Tetradecanoylphorbol Acetate	49-52	tyrosine hydroxylase	Rattus norvegicus	143-163	
1383560-1	1992	We have previously shown that the phorbol ester, TPA, which activates protein kinase C, causes, in PC12 cells, a transcriptional activation of tyrosine hydroxylase (TH), the key enzyme in catecholamine synthesis.	Tetradecanoylphorbol Acetate	49-52	tyrosine hydroxylase	Rattus norvegicus	165-167	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	147-150	tyrosine hydroxylase	Rattus norvegicus	47-49	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	147-150	tyrosine hydroxylase	Rattus norvegicus	70-72	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	147-150	tyrosine hydroxylase	Rattus norvegicus	70-72	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	239-242	tyrosine hydroxylase	Rattus norvegicus	47-49	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	239-242	tyrosine hydroxylase	Rattus norvegicus	70-72	
1383560-8	1992	Trans-activation experiments with plasmids TRE-TH/TK/CAT and -754/-19 TH/pUC18-CAT in PC12 cells showed an increase in CAT activity in response to TPA that correlates with the previously observed increase in TH transcriptional activity by TPA.	Tetradecanoylphorbol Acetate	239-242	tyrosine hydroxylase	Rattus norvegicus	70-72